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Prof. Dr. Mustafa Faruk Usta (K)

Prof. Dr. Mustafa Faruk Usta

Prof. Dr. Mustafa Faruk Usta was born in Rize in 1968. He completed his medical education at Istanbul University, Istanbul Faculty of Medicine (1986–1992) and his urology residency at the same institution (1992–1997). After his military service, he worked briefly at Kartal Training and Research Hospital; since 2000, he has been working at the Division of Andrology, Department of Urology, Akdeniz University Faculty of Medicine.

In 1993, he completed a clinical rotation at the Department of Urology, Heidelberg University, Mannheim. From 2001 to 2003, he worked as an andrology research fellow at Tulane University School of Medicine (New Orleans, USA). Most of his clinical practice is in andrology; his main interests are penile prosthesis implantation, Peyronie's disease surgery and microsurgical varicocelectomy.

He has 67 articles in peer-reviewed journals and numerous international awards. He is a member of ISSIR, ESSM, EAU, AUA, the Turkish Urological Association and the Turkish Society of Andrology.

Education
Primary School (1975 - 1980)
Teielmannschule, Duisburg, Germany
High School (1980 - 1986)
Sakarya Atatürk High School
Medical Degree (MD) (1986 - 1992)
Istanbul University, Istanbul Faculty of Medicine
Residency — Urology (1992 - 1997)
Istanbul University, Istanbul Faculty of Medicine, Department of Urology
Experience
Residency training (1992 - 1997)
Istanbul University, Istanbul Faculty of Medicine, Department of Urology
Military service (1997 - 1999)
Military Hospital, Department of Urology, Malatya
Specialist Physician (1999 - 2000)
Kartal Training and Research Hospital, Urology Clinic, Istanbul
Prof. Dr. (2000 - )
Akdeniz University Faculty of Medicine, Department of Urology, Division of Andrology, Antalya
Clinical rotation — supervising physician K.P. Junnemann (1993 - 1993)
Heidelberg University, Urology Clinic, Mannheim, Germany
Andrology research fellow — supervising physician Wayne J.G. Hellstrom (2001 - 2003)
Tulane University School of Medicine, Department of Urology, Section of Andrology, New Orleans, USA
Memberships
  • International Society for Sexual and Impotence Research
  • European Society for Sexual Medicine
  • European Association of Urology
  • American Urological Association
  • Turkish Urological Association
  • Turkish Andrology Association
Articles
  • International
    1. Kadioglu, A., Tefekli, A., Usta, M., Demirel, S. ve Tellaloglu, S., ‘Surgical treatment of Peyronie’s disease with incision and venous patch technique,’ Int J Imp Res, 11, 75-81, 1999
  • International
    2. Koksal, T., Kadioglu, A., Tefekli, A., Usta, M., Besisik, A. ve Erol, B., ‘Spontaneous bacterial abcess of bilateral cavernosal bodies’, BJU Int, 84, 1107-1108, 2000
  • International
    3. Koksal, I.T., Tefekli, A., Usta, M., Erol, H., Abbasoglu, S. ve Kadioglu, A., ‘The role of reactive oxygen species in testicular dysfunction associated with varicocele’, BJU Int, 86, 549-552, 2000
  • International
    4. Kadioglu, A., Tefekli, A., Koksal, T., Usta, M. ve Erol, H., ‘Treatment of Peyronie’s disease with oral colchicine:long term results and predictive parameters of successful outcome’, Int J Imp Res, 12, 169-175, 2000
  • International
    5. Usta, M., Erdogru, T., Tefekli, A., Koksal, T., Yucel, B. ve Kadioglu, A., ‘Honeymoon impotence: psychogenic or organic in origin?’ Urology, 57, 758-763, 2001
  • International
    6. Usta, M., Baykal, A., Ciftcioglu, M.A., Erdogru, T., Koksal, T. ve Baykara, M., ‘The impact of chronic renal failure and peritoneal dialysis fluids on advanced glycation end-product and iNOS levels in penile tissue: an experimental study’, Urology, 59, 953-957, 2002
  • International
    7. Erdogru, T., Boz, A., Koksal, T., Usta, M., Yildiz, A., Gungor, F. ve Baykara, M., ‘Penile scintigraphy with 99Tc-Human Immunoglobulin G: a novel method for distinguishing the unstable and stable phases of Peyronie’s disease’, BJU Int, 90, 703-706, 2002
  • International
    8. Erdoğru, T., Usta, M., Ceken, K., Koksal, T., Kabaalioglu, A. ve Baykara, M., ‘Is sildenafil citrate an alternative agent in the evaluation of penile vascular system with color Doppler ultrasonography?’, Urol Int, 68, 255-260, 2002
  • International
    9. Usta, M., Koksal, T., Erdogru, T. ve Baykara, M., ’Glans penis necrosis after internal urethrotomy: an unexpected complication’ BJU Int, 90, 351, 2002
  • International
    10. Koksal, T., Erdogru, T., Toptas, B., Gulkesen, H., Usta, M., Baykal, A. ve Baykara, M., ‘Effect of experimental varicocele in rats on testicular oxidative stress status’ Andrologia, 34, 242-247, 2002
  • International
    11. Erdogru, T., Savas, M., Yilmaz, N., Usta, M.F., Koksal, T., Ates, M. ve Baykara, M., ‘Evaluation of penile hemodynamic status and adjustement of treatment alternatives in Peyronie’s disease’, Asian J Androl, 4,187-190, 2002
  • International
    12. Erdogru, T., Ciftcioglu, M.A., Emreoglu, I., Usta, M.F., Koksal, T., Ozbilim, G., Gulkesen, K.H., ve Baykara, M., ‘Apoptotic proliferative index after alpha-1 adrenoceptor antagonist and/or finasteride treatment in benign prostatic hyperplasia’ Urol Int, 69, 287-292, 2002
  • International
    13. Chitaley, K., Bivalacqua, T.J., Champion, H.C., Usta, M.F., Hellstrom, W.J.G., Mills, T.M. ve Webb, R.C., ‘Adeno-associated viral gene transfer of dominant negative RhoA enhances erectile function in rats’, Biochem Biophys Res Commu, 298, 427-432, 2002
  • International
    14. Akkaya, B.K., Usta, M., Esin, O., Koksal, T. ve Karpuzoğlu, G., ‘Primary small cell carcinoma of the kidney’, Urol Oncol, 21, 11-13, 2003
  • International
    15. Leungwattanakij, S., Bivalacqua, T.J., Usta, M.F., Yang, D.Y., Hyun, J.S., Champion, H.C., Abdel-Mageed, A.B. ve Hellstrom, W.J.G., ‘Cavernous neurotomy causes hypoxia and fibrosis in rat corpus cavernosum’, J Androl 24, 239-245, 2003
  • International
    16. Usta, M.F., Adams, D.M., Zhang, J.W., Davis, R. ve Hellstrom, W.J.G., ‘Penile epithelioid sarcoma and the case for histopathological diagnosis in Peyronie’s disease’, BJU Int, 91, 519-521; 2003
  • International
    17. Passarella, M., Usta, M.F., Bivalacqua, T.J., Hellstrom, W.J.G., ve Davis, R., ‘Testicular sparing surgery: a reasonable option in selected patients with testicular lesions’, BJU Int, 91, 337-340; 2003
  • International
    18. Bivalacqua, T.J., Usta, M.F., Champion, H.C., Adams, D.M., McNamara, D.B., Abdel-Mageed, A.B., Kadowitz, P.J. ve Hellstrom, W.J.G., ‘Gene transfer of endothelial nitric oxide synthase partially restores NO synthesis and erectile function in streptozotocin diabetic rats’ J Urol, 169, 1911-1917, 2003
  • International
    19. Koksal, I.T., Usta, M.F., Orhan, I., Abbasoğlu, S. ve Kadıoğlu, A., ‘Potential role of reactive oxygen species on testicular pathology associated with infertility’ Asian J Androl, 5, 95-99, 2003
  • International
    20. Usta, M.F., Bivalacqua, T.J., Sanabria, J., Koksal, I.T., Moparty, K. ve Hellstrom, W.J.G., ‘Patient-partner satisfaction and long-term results after surgical treatment for Peyronie’s disease’, Urology, 62, 105-109, 2003
  • International
    21. Usta, M.F., Bivalacqua, T.J., Yang, D.Y., Ramanitharan, A., Sell, D.R., Viswanathan, A., Monnier, V.M. ve Hellstrom, W.J.G., ‘The protective effect of aminoguanidine on erectile function in streptozotocin-diabetic rats’, J Urol, 170, 1437-1442, 2003
  • International
    22. Koksal, I.T., Usta, M.F., Akkoyunlu, G., Toptas, B., Gulkesen, K.H., Erdogru, T., Tuncer, M., Baykal, A., Ersoy, F., Demir, R. ve Baykara, M., ‘The Potential Role of Advanced Glycation End Product and iNOS in Chronic Renal Failure-Related Testicular Dysfunction: an Experimental Study’, Am J Nephrol, 23, 361-368, 2003
  • International
    23. Koksal, I.T., Erdogru, T., Usta, M.F., Ates, M. ve Baykara, M., ‘Unexpected presentation of syringocele. Acontractile bladder’, Urol Int, 71, 222-223, ,2003
  • International
    24. Hellstrom, W.J.G. ve Usta, M.F., ‘Surgical approaches for advanced Peyronie’s disease’, Int J Imp Res, 15(Suppl5), S121-124, 2003
  • International
    25. Bivalacqua, T.J., Usta, M.F., Champion, H.C., Kadowitz, P.J. ve Hellstrom, W.J.G., ‘Endothelial Dysfunction in Erectile Dysfunction: Role of the Endothelium in Erectile Physiology and Disease’, J Androl, 24(Suppl6), S17-37, 2003
  • International
    26. Koksal, I.T., Usta, M., Erdogru, T., Ates, M., Kukul, E. ve Baykara, M., ‘Incidental adult posterior urethral valve without clinical features’, Int Urol Nephrol, 35, 227-229, 2003
  • International
    27. Erdogru, T., Usta, M.F., Ates, M. ve Yigit, S., ‘Development of Peyronie's disease during long-term colchicine treatment’, Int Urol Nephrol, 35, 207-208, 2003
  • International
    28. Koksal, I.T., Usta, M., Ciftcioglu, A., Erdogru, T., Kukul, E. ve Baykara, M., ‘Sex cord tumor of the adult testis’, Int Urol Nephrol, 35, 365-367, 2003
  • International
    29. Usta, M.F., Bivalacqua, T.J., Jabren, G.W., Myers, L., Sanabria, J., Sikka, S.C. ve Hellstrom, W.J.G., ‘Relationship between the severity of penile curvature and the presence of co-morbidities in men with Peyronie’s disease’, J Urol 171, 775-779, 2004
  • International
    30. Usta, M.F., Sanabria, J., Bivalacqua, T.J., Hellstrom, W.J.G., ‘Feline penile erection induced by topical glans penis application of combination alprostadil and SEPA (Topiglan)’, Int J Imp Res 16, 73-77, 2004
  • International
    31. Bivalacqua, T.J., Usta, M.F., Champion, H.C., Leungwattanakij, S., Dabish, P., Kadowitz, P.J. ve Hellstrom, W.J.G., ‘Effect of combination endothelial nitric oxide synthase gene therapy and sildenafil on erectile function in diabetic rats’, Int J Imp Res, 16, 21-29, 2004
  • International
    32. Bivalacqua, T.J., Champion, H.C., Usta, M.F., Cellek, S., Chitaley, C., Webb, R.C., Lewis, R.L., Mills, T.M. ve Hellstrom, W.J.G., ‘RhoA/Rho-kinase suppresses endothelial nitricoxide synthase in the penis: novel mechanism for diabetic-associated erectile dysfunction’, Proc Natl Acad Sci U S A. 101, 9121-9126, 2004
  • International
    33. Usta, M.F., Bivalacqua, T.J., Koksal, I.T., Toptaş, B., Sürmen, S. ve Hellstrom, W.J.G., ‘The protective effect of Aminoguanidine on erectile function in diabetic rats is not related to the timing of treatment’, BJU Int 94, 429-432, 2004
  • International
    34. Usta, M.F., Bivalacqua, T.J., Tokatlı, Z., Rivera, F., Gülkesen, K.H., Sikka, S.C. ve Hellstrom, W.J.G., ‘Stratification of penile vascular pathologies in patients with Peyronie’s disease and in men with erectile dysfunction according to age: a comparative study’, J Urol 172, 259-262, 2004
  • International
    35. Erdogru, T., Kutlu, O., Koksal, T., Danisman, A., Usta, M.F., Kukul, E., Baykara, M., ‘Endoscopic treatment of ureteric strictures: acucise, cold-knife endoureterotomy and wall stents as a salvage approach’, Urol Int 74, 140-146, 2005
  • International
    36. Bivalacqua TJ, Usta, M.F., Kendirci M, Pradhan L, Alvarez X, Champion HC, Kadowitz PJ, Hellstom WJ: Superoxide anion production in the rat penis impairs erectile function in diabetes: influence of in vivo extracellular superoxide dismutase gene therapy’, J Sex Med 2, 187-198, 2005
  • International
    37. Sezer, C., Koksal, I.T., Usta, M.F., Gulkesen, K.H., Erdogru, T., Ciftcioglu, M.A. and Baykara, M., ‘Relationship between mast cell and iNOS expression in tersticular tissue associated with infertility’, Arch Androl 51, 149-158, 2005
  • International
    38. Kendirci, M., Usta, M.F., Matern, R.V., Nowfar, S., Sika, S.C., Hellstrom, W.J.G., ‘The impact of intralesional interferon α-2b injection therapy on penile hemodynamics in men with Peyronie’s Disease’, J Sex Med 2, 709-716, 2005
  • International
    39. Koksal IT, Yasar D, Dirice E, Usta MF, Karauzum S, Luleci G, Baykara M, Sanlıoglu S: ‘Differential PTEN protein expression profiles in superficial versus invasive bladder cancers’, Urol Int 75:102-106, 2005
  • International
    40. Kendirci M, Zsengeller Z, Bivalacqua TJ, Gur S, Usta MF, Chen M, Szabo C, Hellstrom WJ:‘Poly (Adenosine Diphosphate-Ribose) polymerase inhibition preserves erectile function in rats after cavernous nevre injury’, J Urol 174:2054-2059, 2005
  • International
    41. Bivalacqua, T.J., Musicki, B., Usta, M.F., Champion, H.C., Kadowitz, P.J., Burnett, A.L. and Hellstrom, W.J.G., ‘Endothelial nitric oxide synthase gene therapy for erectile dysfunction’, Curr Pharm Des 11:4059-4067, 2005
  • International
    42. Usta, M.F., Kendirci, M., Gür, S., Foxwell, N.A., Bivalacqua, T.J., Cellek, S., Hellstrom, W.J.G., ‘The breakdown of preformed advanced glycation end products reverses erectile dysfunction in streptozotocin-induced diabetic rats: preventive versus curative treatment’, J Sex Med 3:242-252, 2006
  • International
    43. Bivalacqua,T.J., Deng, W., Kendirci, M., Usta, M.F., Robinson, C., Taylor, B.K., Murthy, S.N., Champion, H.C., Hellstrom, W.J., Kadowitz, P.J., ‘Mesenchymal stem cells alone or ex vivo gene modified with endothelial nitric oxide synthase reverse age-associated erectile dysfunction’, Am J Physiol Heart Circ Physiol 292:H1278-1290, 2007
  • International
    44. Akkoyunlu, G., Erdogru, T., Seval, Y., Ustünel, I., Koksal, I.T., Usta, M.F., Baykara, M., Demir, R., ‘Immunolocalization of glial cell-derived neurotrophic factor (GDNF) and its receptor GFR-alpha1 in varicocele-induced rat testis’, Acta Histochem 109:130-137, 2007
  • International
    45. Koksal, I.T., Ishak, Y., Usta, M., Danisman, A., Guntekin, E., Başsorgun, I.C., Ciftcioglu, A., ‘Varicocele-induced testicular dysfunction may be associated with disruption of blood-testis barrier’, Arch Androl 53:43-48, 2007
  • International
    46. Gurbuz, N., Mammadov, E., and Usta, M.F., ‘Hypogonadism and erectile dysfunction: an overview’, Asian J Androl 10 (1):36-43, 2008
  • International
    47. Koyun M, Baysal YE, Usta MF, Akman S, Güven AG., ‘Evaluation of reproductive functions in male adolescents following renal transplantation’. Pediatr Transplant 13(6):697-700, 2009
  • International
    48. Ralph D, Gonzalez-Cadavid N, Mirone V, Perovic S, Sohn M, Usta M, Levine L ‘Trauma, gender reassignment, and penile augmentation’. J Sex Med 7(4 Pt 2):1657-67, 2010
  • International
    49. Ralph D, Gonzalez-Cadavid N, Mirone V, Perovic S, Sohn M, Usta M, Levine L. ‘The management of Peyronie’s disease: Evidence based 2010 guidelines.’ J Sex Med 7(7):2359-74, 2010
  • International
    50. Serefoglu EC, Yaman O, Cayan S, Asci R, Orhan I, Usta MF, Ekmekcioglu O, Kendirci M, Semerci B, Kadioglu A ‘Prevalence of the complaint of ejaculating prematurely and the four prematüre ejaculation syndromes: rewsults from the turkish society of andrology sexual health survey.’ J Sex Med 8(2):540-8, 2011
  • International
    51. Serefoglu EC, Yaman O, Cayan S, Asci R, Orhan I, Usta MF, Ekmekcioglu O, Kendirci M, Semerci B, Kadioglu A ‘The comparison of premature ejaculation assessment questionnaires and their sensitivity for the four premature ejaculation syndromes: results from the Turkish society of andrology sexual health survey.’ J Sex Med 8(4):1177-85, 2011
  • International
    52. Gurbuz N, Sagdic G, Sanli A, Ciftcioglu A, Bassorgun I, Baykal A, Usta MF ‘Therapeutic effect of combination of alagebrium (ALT-711) and sildenafil on erectile function in diabetic rats.’ Int J Impot Res 24(3):114-21, 2012
  • International
    53. Celik-Ozenci C, Tasatargil A, Tekcan M, Sati L, Gungor E, Isbir M, Usta MF, Akar ME, Erler F ‘Effect of abamectin exposure on semen parameters indicative of reduced sperm maturity: a study on farmworkers in Antalya (Turkey).’ Andrologia 44(6):388-95, 2012
  • National
    54. Akın Y, Şahiner İF, Usta MF ‘The impact of diabetes mellitus on penile length in men undergoing inflatable penile prosthesis implantation.’ Turk J Urol 39(3):161-4, 2013
  • International
    55. Yakut S, Cetin Z, Altıok Clark O, Usta MF, Berker S and Luleci G ‘Exceptional complex chromosomal rearrangement and microdeletions at the 4q22.3q23 and 14q31.1q31.3 regions in a patient with azoospermia.’ Gene 512;157-160, 2013
  • International
    56. Akin Y, Gulmez H, Bozkurt A, Nuhoglu B, Usta MF ‘Usage of neck circumference as novel indicator of erectile dysfunction: a pilot study in Turkish population.’ Andrologia 46(9):963-70, 2014
  • International
    57. Kendirci M, Asci R, Yaman O, Cayan S, Orhan I, Usta MF, Ekmekcioglu O, Kadioglu A ‘Prevalence of male pelvic dysfunction: results from the Turkish society of andrology male sexual health study group.’ Andrology 2(2):219-24, 2014
  • International
    58. Akin Y, Demir D, Görgişen G, Lüleci G, Alper OM, Watanabe CS, Sahiner IF, Usta MF ‘Novel and rare CFTR gene mutations in Turkish patients with congenital aplasia of vas deferens.’ Andrologia 46(2):198-9, 2014
  • International
    59. Gurbuz N, Kol A, Ipekci T, Ates E, Baykal A, Usta MF Chronic administration of sildenafil improves erectile function in a rat model of chronic renal failure. Asian J Androl 17(5):797-801, 2015
  • International
    60. Usta MF, Ipekci T. Penile traction therapy for Peyronie's disease-what's the evidence? Transl Androl Urol 5(3):303-9, 2016
  • International
    61. Çayan S, Yaman Ö, Orhan İ, Usta M, Başar M, Resim S, Aşcı R, Gümüş B, Kadıoğlu A. Prevalence of sexual dysfunction and urinary incontinence and associated risk factors in Turkish women. Eur J Obstet Gynecol Reprod Biol 203:303-8, 2016
  • International
    62. Ozturk S, Sozen B, Uysal F, Bassorgun IC, Usta MF, Akkoyunlu G, Demir N. ‘The poly(A)-binding Protein Genes, EPAB, PABPC1, and PABPC3 Are Differentially Expressed in Infertile Men With Non-Obstructive Azoospermia.’ J Assist Reprod Genet 33(3):335-48, 2016
  • National
    63. Çayan S, Kendirci M, Yaman Ö, Aşçı R, Orhan İ, Usta MF, Ekmekçioğlu O, Kadıoğlu A. ‘Prevalence of erectile dysfunction in men over 40 years of age in Turkey: Results from the Turkish Society of Andrology Male Sexual Health Study Group.’ Turk J Urol 43(2):122-129, 2017
  • International
    64. Gabrielson AT, Le TV, Fontenot C, Usta M, Hellstrom WJG. ‘Male Genital Dermatology: A Primer for the Sexual Medicine Physician.’ Sex Med Rev 7(1):71-83, 2019
  • International
    65. Usta MF, Gabrielson AT and Bivalacqua TJ. ‘Low-intensity extracorporeal shockwave therapy in the treatment of erectile dysfunction following radical prostatectomy: a critical review.’ IJIR 31;231-8,2019
  • International
    66. Kaya Aksoy G, Koyun M, Usta MF, Çomak E and Akman S. ‘Semen analysis in adolescents with familial mediterranen fever.’ J Pediatr Urol 15(4);342.e1-342.e7, 2019
  • International
    67. Campbell JD, Milenkovic U, Usta MF, Albersen M and Bivalacqua TJ. ‘ The good, the bad, and the ugly of regenerative therapies for erectile dysfunction.’ Transl Androl Urol 9(Suppl2); S252-61, 2020
Publications
  • 2002-2003 SMS/Bayer Fellowship Grant — endothelial nitric oxide synthase gene transfer in diabetic erectile dysfunction, Tulane University
  • Jean Francois Ginestie Prize, ISSIR 2002, Montreal — best basic science paper in sexual medicine
  • ESSIR 2002, Hamburg — best preclinical presentation award (MSD)
  • American Society of Andrology 2003 New Investigator Award, Phoenix
  • American Society of Andrology 2003 Thomas S.K. Chang Trainee Award, Phoenix
  • Tulane Health Sciences Research Days 2003 — Dean of School of Medicine Award for Excellence in Research
  • ESSIR 2003 Istanbul and SMS 2003 Denver — best preclinical presentation award (MSD)
  • 2004 AUA/Yamanouchi Best Abstract Prize, Impotence kategorisi, San Francisco
  • 2006 Basic Science Abstract Award, Sexual Medicine Society of North America, Las Vegas
  • ESSM 2014 — best surgical presentation award, Istanbul