It is a chronic autoimmune disease in which the body's immune system attacks its own thyroid gland, leading to an inflammatory reaction (inflammation). By affecting the thyroid gland that regulates metabolism, it is the most common cause of thyroid deficiency (hypothyroidism).
Normally, the immune system protects the body against bacteria and viruses. In Hashimoto's Thyroiditis, however, the immune system makes an error, perceives the thyroid gland as a "foreign organ," and begins producing antibodies that attack the thyroid gland.
These antibodies are called Anti-TPO and Anti-Tg. Due to the effect of these antibodies, chronic inflammation begins in the thyroid gland. over time, the thyroid tissue is destroyed, and the gland becomes unable to sufficiently produce the T3 and T4 thyroid hormones that the body needs. This condition is called Hypothyroidism.